Is illness-free aging possible?

Originally on Science News

Scott Broadbent, a 70-year-old participant in a clinical trial at the Buck Institute for Research on Aging, is testing a ketone ester supplement aimed at burning fat instead of carbohydrates, with potential anti-aging benefits. Geroscience researchers focus on addressing the root causes of aging, aiming to extend healthy years and compress the period of age-related illnesses. Promising compounds include rapamycin, senolytics targeting senescent cells, and ketogenic diets. Clinical trials explore safety and biomarker nudges, but challenges include proving prevention of age-related diseases in humans and addressing potential hype and safety concerns. Despite uncertainties, the geroscience revolution is anticipated, and researchers advise maintaining a healthy lifestyle.

However, obstacles exist in translating geroscience breakthroughs to practical use. Challenges include conducting long-term studies on aging's prevention, navigating FDA approval, and societal attitudes towards age-related interventions. Scientists acknowledge that overselling progress could erode public trust, emphasizing the need for patience and humility as the field continues building data through ongoing clinical trials. While the geroscience revolution is on the horizon, individuals are advised to follow conventional health recommendations, including a balanced diet, exercise, vaccinations, and avoiding tobacco and alcohol, until anti-aging therapies become a more established reality.

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Is aging without illness possible? (2024, January 16). Science News.

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